Ultra cleaning of sterilizing liquids or gases by pressure filtration through one 25 cm (10"), 30 cm (12") or 78cm. (31") cartridge filer. Inlet and outlet connections are at opposite end of the housing, and sanitary Tri-clamp (TC) fittings. The housing can be autoclaved or hot water sanitized with cartridge in place. They can also be in-line steam sterilized with appropriate cartridges.